We played a total of 11 game match ups for our campaign and after many people woundered off we are starting over (3 players active consistantly and 2 others off and on makes it hard to be as fun).
But in those 11 rounds it has worked vary well. There are a few problems that we run into here and there like a lack of ruined building models and using buildings for shooting posissions but these we have taken care of over all to be clear on how they work so isn't a problem anymore.
Once you figure out how to work the game system it works well and I haven't had a problem with it sense then.
It's not the same as playing in person but when you don't have the option it's a great way to play.